Immune · Dogs & cats
Critical Immune Defense Powder — 30-Day Jar
4.3 · 1,902 shopper reviews
Four organic mushrooms plus patented white turmeric in a chicken-flavored scoop.
Powder · 6.34 oz$65.00
Whole-body support, written like a vet’s chart
Introducing the Critical Care line from VetSmart Formulas
Meet the Critical line — our veterinarian-designed trio of all-natural supplements that protect and restore a pet’s health from the inside out. Critical Immune Defense strengthens immunity with certified-organic mushrooms and white turmeric, for dogs and cats alike. Critical Joint Relief eases stiffness with green-lipped mussel and MSM. Critical Digestive Restore brings 10 billion CFUs per dose with prebiotics and enzymes to settle the gut.
We love pets — and we’re committed to giving them the most effective products with real results, no matter the category.
Veterinarian-formulatedMade in the USAFDA-registered, cGMP facilitiesTested by Underwriter LabsNo artificial colors or flavorsWheat-freeSafe alongside most medicationsDogs and catsVeterinarian-formulatedMade in the USAFDA-registered, cGMP facilitiesTested by Underwriter LabsNo artificial colors or flavorsWheat-freeSafe alongside most medicationsDogs and cats
Top of the chart
Targeted support for the pages vets fill in most often.
Joints · Dogs
Critical Joint Relief Soft Chews — 60 Count
4.5 · 50 shopper reviews
Green-lipped mussel and sea cucumber in a chew they take like a treat.
Soft chew · 60 ct$49.00
Digestion · Dogs
Critical Digestive Restore Probiotic Soft Chews — 60 Count
4.0 · 48 shopper reviews
Prebiotic, probiotic and enzyme blend — 5 billion CFUs in every chew.
Soft chew · 60 ct$42.00
Oral & Coat · Dogs & cats
Total Oral Care Breath Spray with Aloe Vera
4.2 · 2,235 shopper reviews
Two sprays in the water bowl — fresher breath without a toothbrush.
Spray · 4 oz$18.95
Sets · Dogs
The Critical Line Bundle — Immune, Joint & Digestive
New to the chart · three best-rated formulas in one box
Immune Defense, Joint Relief and Digestive Restore — the full Critical line in one box.
3 jars$117.00
Immune · Dogs & cats
Critical Immune Defense Powder — Large 90-Day Jar
4.3 · 1,902 shopper reviews
The same formula in one 19 oz jar — replaces our old three-pack of small jars.
Powder · 19 oz$180.00
Oral & Coat · Dogs
Protect Anti-Itch Shampoo for Dogs
4.3 · 83 shopper reviews
Cedarwood, rosemary, lemongrass and coconut — plant-based relief from scratching.
Shampoo · 8 oz$14.95
Joints · Dogs
Advanced Hip + Joint Complex Chewable Tablets
4.5 · 985 shopper reviews
The original tablet that 985 shoppers reviewed — the recipe the soft chew grew from.
Chewable tablet · 60 ctBack soon
Digestion · Dogs
Probiotic Nutrient Enhancer Capsules — 60 Count
4.5 · 144 shopper reviews
15 billion active cultures, meant to ride alongside our joint formula.
Capsule · 60 ctBack soon
Oral & Coat · Dogs & the home
Protect Home + Dog Anti-Itch Spray
4.0 · 24 shopper reviews
The shampoo’s essential-oil blend, for fur, beds and carpets.
Spray · 8 ozBack soon
Four systems. One chart.
Designed for the veterinarian’s office first.
VetSmart Formulas began as a line made for vets to prescribe — so every formula carries the clinical strength, quality and consistency a veterinarian demands. We make them in the USA, in FDA-registered facilities that follow cGMP standards, with no artificial colors, flavors or fillers. Then we put them where pet parents can reach them.
The care chart
Find the sign. Read across.
How we’d match the most common signs to a formula and a starting dose. Your vet has the final word.
| Sign on the chart | Page | Formula | Dose | Shop |
|---|---|---|---|---|
| Slowing down on walks, stiff after naps | Joints | Joint Relief soft chews | 1 chew daily <25 lb · 4 chews twice daily 100+ lb | |
| Senior years, recovery, or a worrying diagnosis | Immune | Immune Defense · 30-day jar | ¼–3 scoops twice daily, cats included | |
| Gas, loose stools, a sensitive stomach | Digestion | Digestive Restore soft chews | 1–4 chews daily · 5B CFUs per chew | |
| Breath you notice from across the room | Oral care | Total Oral Care spray | 2 sprays in a full water bowl | |
| Scratching, licking, hot spots | Coat | Protect shampoo | Lather, rest a minute, rinse | |
| More than one of the above | Whole chart | Critical Line bundle | Scoop at breakfast, chews at dinner | |
Found in the jar
Every formula starts with ingredients we can name — and show you.
The Critical Line bundle
Whole-body health needs whole-body critical support.
All three Critical formulas together: the mushroom and white turmeric immune powder, the green-lipped mussel joint chew and the probiotic digestive chew. It’s how we’d set up a senior dog’s routine from day one.
$117.00three jars, one routine
What’s in the box
Every family member counts.
Reviews from pet parents
5,471+ shopper reviews across the line
Immune Defense · 30-day jar
★★★★★
Twice a day on her kibbleOur 12-year-old lab mix eats the powder without noticing it’s there. Her energy on walks is back to where it was last spring and her vet is happy with her bloodwork.
Joint Relief soft chews
★★★★★
He takes the stairs againThe chews go down like treats — no more hiding pills. After about five weeks our shepherd stopped hesitating at the bottom of the stairs.
Total Oral Care spray
★★★★★
Two sprays in the bowlI can’t brush my cat’s teeth, full stop. Two sprays in the water every morning and her breath is genuinely better. Also using it for the dog.
Digestive Restore soft chews
★★★★☆
Calmer stomach, better stoolsOur boxer has a touchy gut. Two chews a day and the midnight emergencies have mostly stopped. Knocked off a star only because he wants more of them.
Protect shampoo
★★★★★
Stopped the hot spot cyclePlant-based and it actually works — the scratching calmed after the second bath and his coat is softer than with the oatmeal stuff we used before.
Immune Defense · 90-day jar
★★★★★
Big jar, one less reorderWe give the immune powder to both cats and the old beagle. The large jar lasts ages and the scoop chart made dosing everyone easy.
Composite stories written from the themes shoppers mention most often in public reviews.
VetSmart Formulas: vet-formulated dog and cat supplements, one page of the chart at a time
An immune supplement for dogs and cats, dosed like a prescription
We wrote Critical Immune Defense for the pets vets worry about most: seniors, patients in recovery, dogs and cats with a diagnosis that needs backup. The powder blends four certified-organic medicinal mushrooms — turkey tail, reishi, shiitake and maitake — with a patented white turmeric root extract, and we dose it by body weight from a five-pound cat to a giant-breed dog. It’s chicken-flavored and hypo-allergenic, so it disappears into the bowl twice a day.
Hip and joint supplement for dogs with green-lipped mussel
Stiff mornings, slow stairs and a shorter walk are the first lines on the joint page. Our Critical Joint Relief soft chews carry New Zealand green-lipped mussel, sea cucumber, glucosamine and MSM, with vitamins C and E for antioxidant cover — more glucosamine and MSM than typical joint chews. We make them for senior dogs, large breeds, overweight dogs and dogs back from surgery, and they sit comfortably alongside most medications.
Probiotics for dogs that help everything else absorb
Digestive trouble drives about one in five vet visits, and a gut that isn’t working wastes whatever else you feed. Critical Digestive Restore is our dog probiotic soft chew: prebiotic chicory root, multi-strain probiotics at 5 billion CFUs per chew and enzymes from papaya and pineapple, plus pumpkin for fiber and broccoli seed for skin and coat. Given with our immune and joint formulas, it helps the whole routine do its job.
Dog breath spray and anti-itch shampoo for the outside pages
Not every entry on the chart needs a chew. Total Oral Care is our breath freshener for dogs and cats — aloe vera, peppermint, cloves, honey and cinnamon, two sprays in the water bowl — to keep plaque and tartar in check between dental cleanings. For scratching and hot spots, our Protect anti-itch dog shampoo uses cedarwood, rosemary, lemongrass and coconut oil, with no soap, parabens or artificial fragrance. Everything we make is produced in the USA in FDA-registered, cGMP facilities and tested by Underwriter Labs.
Yes — the Critical line was designed to be given together. Many owners give the immune powder in the morning and the joint and digestive chews with dinner. If your pet takes prescription medication, tell your vet what you’re adding.
Critical Immune Defense powder and Total Oral Care spray are made for dogs and cats. The joint chews, digestive chews and the Protect line are dogs-only.
Oral care spray works on breath from the first bowl. Digestive support usually shows within one to two weeks; joint and immune support are long-game formulas, and most owners judge them after four to eight weeks of daily use.
They’re wheat-free, contain no artificial flavors, colors or fillers and no added soy. Check the full ingredient panel in the product photos if your dog has a specific protein allergy.
In the USA, in FDA-registered facilities that follow current Good Manufacturing Practices, with third-party testing by Underwriter Labs.